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Archive for February, 2008.

Despite that Acomplia Sales are Low, Sanofi Has High Hopes

Posted on February 26th, 2008 by Kate in Acomplia info

With sales of Acomplia (rimonabant) is low in the several dozen countries where it is on the market, Sanofi-Aventis executives had little to say about their pioneering obesity treatment in a report to analysts on Feb. . But that hardly means they have given up on the CB-1 receptor antagonist.

Instead, Sanofi unveiled plans to make at least three presentations at major U.S. and European medical meetings during 2008 on the results of clinical trials of Acomplia as a treatment for heart disease and diabetes.

And as a strong indication that the results Sanofi Aventis is seeing from the diabetes trials continue to look really good, the French company reiterated that it plans to seek for FDA approval of rimonabant (to be called Zimulti in the United States), this time for treatment of diabetes, in 2009.
So where do things stand on the hopes of millions of obese and overweight people that rimonabant would become the next blockbuster pill for treatment of obesity?
Well, Sanofi reported that fourth quarter sales of Acomplia worldwide totaled 21 million Euros (approximately US $30.6 million) — unchanged from the 21 million Euros in sales that Sanofi reported for the third quarter of 2007.

He said results of the ARPEGGIO study, evaluating rimonabant in combination with insulin for treatment of diabetes, will be presented to the American Diabetes Association at its annual meeting in June 2008.

Cluzel also said Sanofi is awaiting further recommendations from the FDA on the tracking during clinical trials of depressive side-effects associated with rimonabant — the problem that led in mid-2007 to Sanofi’s withdrawal of its application to have Zimulti approved for sale as an obesity drug in the U.S.

“As for side effects, we are in conformity with FDA recommendations particularly when it comes to psychiatric effects, suicidal ideas are very much in the limelight, and of course, this applies for the whole class of CB1s as well as for antiepileptic pills and antidepressives as a class,” Cluzel declared.

“So we are waiting to see what the FDA recommendations will be,” he also said.

So Acomplia will be on the american market sooner or later as an weight loss pill or as a pill that treats diabetes.Will hope that happens really soon because millions of people need it!

Trust Rimonabant for Complete Obesity Solution

Posted on February 10th, 2008 by Kate in Rimonabant and obesity

Learn to love your body and if you are really serious about your body then you even in dreams don’t want those extra kilos of unwanted fat to present on it. Well people adopt numerous methods like starving and exercising to shed off their excess fats and overcome overweight as well. But its also true that majority of them fail to achieve the desired results. In vain they become either depressed or suffer in anxiety. They see no ways to end their woes.

Burning of weight is not an easy task. Besides maintaing a balanced diet and exercise daily is not an easy affair for everybody. There are certain obligations which may come in the way of their daily life schedule and this may hamper their daily weight loss journey. But choice of effective weight loss medication like Rimonabant along with well planned weight loss program can be very beneficial. One such drug or diet pill that can be very effective is Rimonabant. This drug is well approved by the US FDA as an anti obesity diet pill which comes with success record that assures obese patients to loose significant amount of weight and keep them free from fats.

Rimonabant is a weight loss drug which belongs to the class of anorectics which acts on the central nervous system to inhibit the hunger centre and hence suppresses the appetite .It is recommended that Rimonabant should be used for short-term, normally up to 12 weeks while following non- pharmacological approaches to weight loss such as healthy dieting and exercise.

It’s a prescription diet pill and only the doctor can determine the right amount of dose for a particular individual. Generally three doses above 120 mg after 30 mins of every meal are what a doctor suggests. But depending on your obesity situation, the doses may change. First timers may suffer from bowel changes like gas with oily discharge, inability to control your bowel movements, constipation, and indigestion. But no major side affects has been recorded till date. Pregnant women must go for a doctor consultation before taking Rimonabant.

Maintaining a healthy eating plan with a routine exercise in conjunction with Rimonabant will lead you to a fat free life.